| Sl.No. | Name of Chief Ministers | From | To | Party |
|---|---|---|---|---|
| 1 | Edappadi K Palaniswami | February 16, 2017 | Present | AIADMK |
| 2 | O. Panneerselvam | Dec 6, 2016 | Feb 16, 2017 | AIADMK |
| 3 | J. Jayalalithaa | May 19, 2016 | Dec 5, 2016 | AIADMK |
| 4 | J. Jayalalithaa | May 23, 2015 | May 19, 2016 | AIADMK |
| 5 | O Panneerselvam | 29th Sep 2014 | May 23, 2015 | AIADMK |
| 6 | J. Jayalalithaa | 16. May. 2011 | - | AIADMK |
| 7 | M. Karunanidhi | 13. May. 2006 | 15. May. 2011 | |
| 8 | J. Jayalalithaa | Mar 2, 2002 | 12. May. 2006 | AIADMK |
| 9 | O. Panneerselvam | Sep 21, 2001 | Mar 1, 2002 | AIADMK |
| 10 | J. Jayalalithaa | 14. May. 2001 | Sep 21, 2001 | AIADMK |
| 11 | M. Karunanidhi | 13. May. 1996 | 13. May. 2001 | DMK |
| 12 | J. Jayalalithaa | Jun 24, 1991 | 12. May. 1996 | AIADMK |
| President's rule | Jan 30, 1991 | Jun 24, 1991 | ||
| 13 | M. Karunanidhi | Jan 27, 1989 | Jan 30, 1991 | DMK |
| President's rule | Jan 30, 1988 | Jan 27, 1989 | ||
| 14 | Janaki Ramachandran | Jan 7, 1988 | Jan 30, 1988 | AIADMK |
| 15 | V.R. Nedunchezhiyan (acting) | Dec 24, 1987 | Jan 7, 1988 | AIADMK |
| 16 | M. G. Ramachandran | Feb 10, 1985 | Dec 24, 1987 | AIADMK |
| 17 | M. G. Ramachandran | Jun 9, 1980 | Nov 15, 1984 | AIADMK |
| President's rule | Feb 17, 1980 | Jun 9, 1980 | ||
| 18 | M. G. Ramachandran | Jun 30, 1977 | Feb 17, 1980 | AIADMK |
| President's rule | Jan 31, 1976 | Jun 30, 1977 | ||
| 19 | M. Karunanidhi | Mar 15, 1971 | Jan 31, 1976 | DMK |
| 20 | M. Karunanidhi | Feb 10, 1969 | Jan 4, 1971 | DMK |
| 21 | V.R. Nedunchezhiyan (acting) | Feb 3, 1969 | Feb 10, 1969 | DMK |
| 22 | C. N. Annadurai | Jan 14, 1969 | Feb 3, 1969 | DMK |
| 23 | C. N. Annadurai | Mar 6, 1967 | Jan 14, 1969 | DMK |
| 24 | M. Bakthavatsalam | Oct 2, 1963 | Mar 6, 1967 | INC |
| 25 | K. Kamaraj | Mar 15, 1962 | Oct 2, 1963 | INC |
| 26 | K. Kamaraj | Apr 13, 1957 | Mar 1, 1962 | INC |
| 27 | K. Kamaraj | Apr 13, 1954 | Mar 31, 1957 | INC |
| 28 | C. Rajagopalachari | Apr 10, 1952 | Apr 13, 1954 | INC |
| 29 | P. S. Kumaraswamy Raja | Jan 26, 1950 | Apr 9, 1952 | INC |
